[BRIEFING.COM] The S&P 500 (-0.71%) is in second place on Tuesday afternoon, down about 43 points.
Briefly, S&P 500 constituents Palantir Technologies (PLTR 70.97, -4.95, -6.52%), Take-Two (TTWO 182.79, -6.19, -3.28%), and Southwest Air (LUV 32.79, -1.04, -3.07%) dot the bottom of the standings. PLTR falls in part due to executives disclosing stock sales overnight pursuant to 10b5-1 trading plans, TTWO slips after BofA Securities note suggesting risk to Take-Two's mobile growth targets amid sluggish in-app purchase trends.
Meanwhile, vaccine firm Moderna (MRNA 48.54, +5.97, +14.02%) is today's best-performing constituent, reacting favorably to news of the first death reported in the U.S. from H5N1 bird flu.